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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43a6d9096c005c63e91265492a5ca036e3bc448ba1f5de57ea5bd399e85b5971' 
  AND token = 'i26j1/rexca1lZH+1eRPLkIFzYKM1BR/nd4nZ9uoe1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}