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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c10d6905f6e463ff327fa48987dd4e598a4934fd2f04f95dffbf10ef359fc15' 
  AND token = 'GIICsil4HWDr0OsTEG9+gJvEjmicRKNoESophj9Xxfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}