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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c2062ff7f8a3bee34a281bb967ab30b8a4e5ccfc569ea39645496a15387d30d' 
  AND token = 'JEis0HxFa6BmOo6Gu3c1DWcUYe1EMP2auHcfouCyEZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}