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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81d41921f7a351808a4615b0387d9a308831a9405dcc0a5472b60aa55cb46ff9' 
  AND token = '0YE4VD8VZ8PdXGwvA/3aGNZgnKj/hmNxC1ed1a9agBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}