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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc4ace87f1d481729f9e711a01834cced99735d556a56e4300c9d6bc5b8c4f0c' 
  AND token = 'hRqQ8C9VCEJaVWR5vB6RDFSRWqiJQsQmZy3a227X3mA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}