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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f6d9983c2c471e1913a8add767d2c129f9d63bef30073bdc56a1b4e11fe2604' 
  AND token = 'TzZMz3e1hb9eUmm3T85vXle/5VHmgnOqMl7g8NKta0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}