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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a68f0e1705d18958e62de334006ac712d2c4382d86b002855b9ba293e2517c3' 
  AND token = 'Tw+XuigfgF2CgWLFcsfffS5MWE4Hy4i0UmlQL7ZjDSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}