SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5e89b302a3b926b8f2dd5c4e9a74e155647a91e9a988d91d4568101e3887619' 
  AND token = 'zQ2fEO9ZHx1fG4sE48pkixAhExd6olyPfuc2Ef8zWNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}