SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '493e7aff6f4e4d950cecfee7be7febc8e5711c5cc5bb9512e15eceb2308b444c' 
  AND token = 'rl8C61gJI3KtX8oLbxz3jhKnzmBNO6BFN6Nn/3v81X8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}