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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '000fb60b6b9bef5ae95d6f5dbe169c9804b93704109ec5dea37dfbf87f789ce4' 
  AND token = 'X7BcU3BcitIUrpmq+KywM1W6Xf4Rm6N4KHDz7KhQHU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}