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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46a830f34d5f26ad820d74123842399543eac64bf9c51b00f4df35e9d27c7ca7' 
  AND token = 'ETIwi3Nz7gp3l6/skheA0wUWS2xVtevhTaAe5cSRjPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}