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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '050aabafaa01694c5360df2fa0f462a389ecd0e07b476119a4c17b206050a123' 
  AND token = 'aXCB3mZ+dBKKN5/CSPq/T0mcDKtWjqSK+92IxihpTc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}