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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '601cb668a4a858e0d5e41d2f3abc99e14fd541a2460e11e007886dc6542a33e3' 
  AND token = 'hJ67RC2+5iqfXxt6TKFaTiQ6L7Pv5D1FucUV9zHi75I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}