SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dddc159196392ed7251ecde04bf4a39056bf0ccf7c5e6d1ab589dbd87f37b7ab' 
  AND token = 'yF4yn4/QrUziq35eRgDq2+lxWIW00a3KxoWy7oRv9A8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}