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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '813c200248f902e2c2a04dc148f4aeaa006cf26e6193a363050a48dd3419362a' 
  AND token = 'W9Pjg1WS6QLVW4EYUizHs6bqpt3CgZzoY2rsn4nCOOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}