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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'beb216ca50e65bf2cfc4087a2c8eef6ffc68623327199fbb66734e653ec777a8' 
  AND token = 'ZoleOxAaKbKyt8VxGEzmBd8KS1tuGTACZn2FRsFgUUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}