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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ab2dfaa18c4593e6dd2b42c4299798e31f3e80ba2bee8898e815b6088676420' 
  AND token = 'FOVrgONxvPax1ky78pfGG9dn9DFErRTcwd4KEJFKdDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}