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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08c43c748802de33433770773fcb25c2d1d02239f0ad7c7e9ea51ad27cffc714' 
  AND token = 'iPZKRvNP/ShmU48G4dgWa8zdIs8j9yqWOC6uUtgS3h4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}