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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71db66e31b6db2dc3e49213bba053ee9ea527dc99deb590a87c89b9fcd667cd8' 
  AND token = '09NkOOec0UtAjJoPF4bgyXmJuO89hKTgVr4+jxLG3Cs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}