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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28be0fc8b7ba28fea802e4b9ea8a88d02ed540c4135d47eccabb146370dd2192' 
  AND token = 'EYtES1hvNXaP4nrbFjH+hU1rQ6tWkXYUBb9BuoZGyrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00085

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}