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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a88263d9ca9b654e6c4857cbb9edfe5cb454128f23c95355419a5b17e2ca7c6' 
  AND token = 'oOwTNs1t6Udtn9nLeayKG86hiTVDHy9kjLd1JJBnCOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}