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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b40e5b61914fb68acb03a251d30d8fb8e727233514f6ec4c51d22aa1e5f1c8b' 
  AND token = '4tbNFLoZFiTJtCRCQN3OhP8EuNNqqTMeZWbWl9c2SiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}