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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '779b729189559075e86eda16361b28ab55ec26be05eb33ffd7acdae4a5d43f57' 
  AND token = 'GcfPtnkA+aFR1Izzb12i+rqUSVb0tUOR1mKn9dALVoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}