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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06606c9ce25f9a979ef281b240fb1ba8fa18d5bd0f4ef9c60ec228b16255326c' 
  AND token = 'a+VhbUFY9NxiJ4gOK7+yOaWsnoUzSeeqw+2vJdbFoHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}