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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b600c083111ab562ee972b0650e0a237a7fed7983d71db1db66de4a9d497eee4' 
  AND token = 'W6a7AUKUrdNaOM3A0tf5GCTV0WlPkQAQNRMNnYowcxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}