SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7909ccf71d94ceb1a03b8466471705ae78b8c6e1b0fddb6f59637854a903c288' 
  AND token = 'n0klY/+CH9kCU9s8MVuJOGIHNsFXbGU0LhbbGwtejww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}