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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c15e43cf2b3c3427096a22be0b408af0d4730a37fb6d6bf0db33df4a10e866c6' 
  AND token = 'HtytHCodDHEt0d1xj7OUbFFrn5UIVkBMc3m0qQQuUQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}