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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ec4ce7c7de0ec467704cba72d88d309696954f6028fd9e8b050db3dbd0aaf20' 
  AND token = 'j3bOAJzzoUdH0Ghpj6k1NlOD4I15+SBXF4TGQmEEc10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}