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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab7d5ae1619a072cf36f9ee0264200a9417629178a73f04a807018d4199ec0fb' 
  AND token = 'FkTjCKbx442P3PNfKzwFqt6uwIbhtX9+Rvo6XcgwTw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}