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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2b0a4dbd65b313bd72465746f88d7bccd6da549763d1c54d95604b8653adc46' 
  AND token = '1tMP4pj7ECJ4X7z+D0C5na52lxce+HuIPmVX91vEMgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}