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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c8a8ee2499ffe91f277089fdd2091b71e6417ddc09d8e164c47b94733ee7354' 
  AND token = 'JiiIXOz5ppFVz7VMOfLIbBTXtaZcOtg0ZPG5xfaPBsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}