SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81b2135a44e63cabfa1abcf5228280f38e98a27e6c4122e454d7aa97b50c71d0' 
  AND token = 'L8t/mV7MgTvxkb9mCUo0CbCu9ys5wODeo5fGcojVGzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}