SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14a5aa9254ba9fbb3921a469ffac7ddc7b22f679e7952abe542ab350bba9f138' 
  AND token = 'LNDBdo+3IdYGHO8dl1c/tKV7h5BB1/+E2SjgU05vShE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}