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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d0e347423d775f936b6fb57ba72901927450e77d037eb784e46f17c2c221d13' 
  AND token = '/rMX6F+e8WuIySuK8ZQudioOBNwKhykhw74c67IguO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}