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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af46eda763e428c425b0b020231aa6bf00feb80e621e428e49c73a01d7567f4f' 
  AND token = 'FB8k39R6YpCrlm4JW40DxOc+UcGYPHyacjk1P1iazu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}