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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43fb77bfba4dba54e6cd21a72de934b7dbfb7ad16b12f8e349cf7824c614a871' 
  AND token = '/kRxGeQT6XPJ+P/PlKiXTmsDZp3y7Av9qmtghE7IgI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}