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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c21a1e0e0c1325852ea0900e38be76bd0ccf0608f86b2eeab66938836e522e8a' 
  AND token = 'FwSsY5LvzMeeI2ESu0Y6ICMLY0NWkK6zhMt+RRFrRyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}