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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21264faf6e5741a625fa29e04bd6b8019109458553ae0e560238599a497a8e10' 
  AND token = 'CCqVoHqTc7UGt9Bk4CPXyumsP49fY1U8md/K0jkhtsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}