SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '606f1fdd1ad4f2774434d627e60a2e1b431eebd7768966b3405194dc3c5f288c' 
  AND token = 'HVnPMM1/eG2jGeVJ3oYpCIjABXP/NeJ0TmggqmqezvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}