SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e95eab567b6e7fe193f2b6d74bd0cca6184cde23700b1061e79ed47fc477eab' 
  AND token = 'KpwdS4+K7gyUN9ZzMtXbtpr0PDUwfPR/RRXj3GEZzQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}