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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49c1e15765fffbb0af04160db88e1443611a5ba1c390c0694acbc4c3338bf167' 
  AND token = 'qn4wwX5aqdGYvUw95+hvZpIClcidi+ONRDe2CxAAZBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}