SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f6a229942dcbcd6612fb516b1eb9f5eccd57758688b37c129b00cda7d6cb4a9' 
  AND token = 'JV0iaP0yC4XEs0kWrOVA3oMkzqPHDJ5cddB1Slc3Vw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}