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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bdfde45a6ce14d3a6d6960fb0fac7f5017f4e0001477a22f9acef9d91c036eb4' 
  AND token = '+B/Nzkx4Sr3Eo2COAsudsGWbBoD6M6QDIEoXhZqF3uo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}