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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a31aae6d174868a6dd2db8da1d03d8d6372b12192a169a8bccbd19a108338b0' 
  AND token = 'xdoNR1/k42jzgDKp1GunZf1ZOGKLpmKHjkL/ufnIrZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}