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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fad1212d8321d5da6cd210253d0655f3bc4b58a58652e32613052ebdbd5d01b' 
  AND token = 'jQAxTZN2QysOzlLoFoN3am9cYrNj6iR7fm0znT8dex4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}