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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b66a9ba01f2cda356f9dc20c71a5aea751c36fb5d5e54225bf813f30544df981' 
  AND token = 'OaL/Tb+vlOa+ENEDrhytoMEvbQyy/KAPEgfQ6KTRP5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}