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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd61e9286fcb8e6fe356c5ec385b7e5581b4245fc12d040cbcce568241e12bd26' 
  AND token = 'FKtGOISLdpMpx75VGse0YpW0xbH8IqOuwljL2OIqvvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}