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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '861ac6fe1e4b2f25f20a2f8c04f50a31354189596324e8e28cf826d3b36f9214' 
  AND token = 'bZ89enDaSSS8PBZSyaIdZDFrpAST1CD5Rl45D8/ahJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}