SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67ef9fb2506d61f0bd874c2c285afa024fbdb2f09a6f6ef4a14e13fcc736d4ed' 
  AND token = 'yGi9bUMfToK0qyT1kSUrCVboRkOh6hkFlZnNlQI4+vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}