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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c549d6f66913d2f1886c4a28764922c669f1941715271eafe0000153c69f063' 
  AND token = '6tPDPOTk5M3i6uYTvSAj+FEmC3u30raJpK+wOVFjmGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}